Bacillus thuringiensis var. thuringiensis

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Bitoxybacillin™ is a biological insecticide meant to propetct plant from insect pests: red spider mite, Colorado beetle (larvae instar I-III), worms of cabbage, grass, meadow, silkworm, geometrid, apple, ermine moths, cabbage white, turnip and whitehorn butterflies, leaf rollers and others.
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Bitoxybacillin™ active agents are bacterial spores, protein crystalls (delta-endotoxin) and heat-stable ß-exotoxin of Bacillus thuringiensis var. Thuringiensis. Inert fillers provide product integrity, flowability, adhesiveness and stability.
MODE OF ACTION Crystalline protein of Bitoxybacillin™ determines its intestinal action. After ingestion by pest, the product causes intestine dysfunction, thus lowering pest feed rates. Product ß-exotoxin, permeating across intestinal tract and skin cover into insect body, supresses RNA synthesis in pest cells. Pest mass mortality begins on the 3rd-7th day. Sublethal doses od Bitoxybacillin™ inhibit feeding, break metamorphosis periods, decrease female prolificacy and next generation viability (antifeedant and metatoxical effects).

Product main characteristics
Item Standards
Appearance and colour Pale-beige to brown powder
Bioloical activity,
UA/mg, n.l.t.
Exotoxin content,% 0,6-0,8

Bitoxybacillin™ consumption rates to control most abundant leaf-eating pests
Crop Pest Consumption rate
Greenhouse crops Red spider mite 10-30 kg/ha
Flowers and herbs Meadow, noctuid, geometrid moths leaf rollers, painted lady 2-3 kg/ha
Nightshade family Colorado beetle 2-5 kg/ha
Vegitable crops White butterflies, meadow, noctuid, pyralid moths 1-2 kg/ha
Fruit crops and berries Leaf rollers, fall webworm, apple worm, whitehorn butterfly, sawflies, red spider mite, pyralid, geometrid and silkworm moths 2-5 kg/ha
Grapes Grape moth 6-8 kg/ha

In agriculture, Bitoxybacillin™ is applied to vegetable and fruit crops and medicinal herbs. 
Bitoxybacillin™ is applied by means of plant spraying with any available ground spraying devices. 
Product is recommended to be applied in dry weather in the morning or evening. Maximum protective effect of Bitoxybacillin™ application is achieved when treating trees and bushes at early (I-III) larvae instar at (18-30)°С air temperature. Bitoxybacillin™ is safe for people, warm-blooded animals, fish, hydrobionts, bees and entomophages when applied at proper consumption rates. 
  • Effectively destroys vide variety of lepidopterous insects, red spider mites, Colorado beetle worms and other pests.
  • Is not phytotoxic, not accumulated in plants and fruits
  • Ensures eco-friendly and safe products
  • May be applied at any stage of plant growth
  • Safety interval is 5 days, thus, crops may be treated shortly before harvesting
  • Is compatible with chemical pesticides and biological products when applied in tank mixtures and within integrated plant protection system
  • May be applied to solve the problem of pest resistance to chemical pesticides.

Commodity form: powder Bitoxybacillin™ P 
Shelf life: 18 months at (-30) - (+30)°С. 
Packaging: packed by 15 kg, 20 kg into hermetically sealed polyethylene bags.


In December 2012 "Sibbiopharm" received a certificate of international certification body TUV NORD CERT (Germany) according to the quality management system ISO 9001: 2008. The company received the right to use the mark TUV NORD CERT

Since 2009, "Sibbiopharm", entered in the Federal Register of reliable suppliers.

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